Palestinians killed in Israel Gaza air strike
Israel's military said it targeted Hamas weapon-making facilities. Palestinian officials said a woman and child in a nearby house were killed.
Later, three Israelis were stabbed near Hadera - the latest in a spate of such attacks amid mounting tensions.
West Bank medical officials say a boy of 13 was shot dead by Israeli forces in clashes near a Jewish settlement.
Earlier in the West Bank, a Palestinian woman set off an explosion at a checkpoint, Israeli police said.
She was stopped while driving early on Sunday near another settlement, Maale Adumim.
Security forces said she shouted Allahu Akbar (God is great) before the explosion.
The Shin Bet internal security agency said she tried to ignite a gas cylinder using flammable materials.
"We are not talking about an explosive device," a statement said.
Following Sunday's air strikes, Israeli army spokesman Lt Col Peter Lerner said: "The IDF holds Hamas responsible for any act of aggression from the Gaza Strip."
There have been weeks of tension over access to a site in East Jerusalem sacred to both Jews and Muslims.
Palestinians fear Israel plans to change arrangements at the al-Aqsa mosque/Temple Mount compound, where Jews are allowed to visit but not allowed to pray - something Israel insists it will continue.
Late on Saturday, US Secretary of State John Kerry expressed "deep concern" over the situation.
He made separate phone calls to Israeli PM Benjamin Netanyahu and Palestinian Authority President Mahmoud Abbas.
Mr Kerry "stressed the importance of upholding the status quo in word and deed" at the site, the state department said.
He offered his support in efforts to restore calm, but both men blamed the other side for the rising violence.
Mr Netanyahu "made it clear that he expects the PA [Palestinian Authority] to stop its wild and mendacious incitement, which is causing the current wave of terrorism",his Twitter account said.
Mr Abbas told Mr Kerry that Israel should stop settler "provocations", which he said were carried out under Israeli army protection, his office reported.
The violence has spurred talk from Hamas, which dominates Gaza, of a new Palestinian intifada, or uprising.
But the clashes have not yet reached the scale of previous intifadas, with no clear mass movement or leadership so far emerging.
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